Stem cells are classified as embryonic or adult. Adult Mesenchymal Stem Cells (MSC) are multipotent cells that can differentiate into a variety cell types, such as fat cells, cartilage cells, bone cells, tendon, muscle cells, blood vessel cells, or nerve cells. Adult MSC are in bone marrow (BMMSC), fat, umbilical cord, or muscle tissues. The MSCs have a great capacity for self-renewal, adherence, ability to differentiate into many cell types, and have a fibroblast-like morphology. MSC have enormous clinical applications for tissue repair in bone or cartilage, chronic kidney failure, and modifying immune function. The combination of MSC with biomaterials scaffolds is used for constructing tissues and cell delivery.
Services (in-house)
- Isolation of Bone Marrow-Derived Mesenchymal Stem Cells from dogs
- Expansion of isolated Canine Bone Marrow-Derived Mesenchymal Stem Cells
- Preparation of Canine Bone Marrow Mesenchymal Stem Cells for injections
- Storage of Canine Mesenchymal Stem Cells in Liquid Nitrogenodes
Research
- Cekanova M#, Lucy K, Geiser D, Millis D, Legendre A, and Whitlock D: “Hyperbaric oxygen treatment affects canine mesenchymal stem cells in vivo” 2nd North American Veterinary Regenerative Medicine Conference in Lexington, Kentucky; June 2 – 4, 2011
- Westling M, Tanco V, Rathore K, Sonntag A, Galyon G, Wright L, Carter A, Legendre A, Millis D, and Cekanova M#: “Bone marrow-derived mesenchymal stem cells (BMMSC) for the treatment of canine osteoarthritis.” The 6th Annual Comparative and Experimental Medicine Research Symposium UT, Knoxville, TN, May 20-21, 2012 poster #40
- Cekanova M#, Geiser D, Millis D, Whitlock D, Legendre A, and Dhar M: “Effect of hyperbaric oxygen treatment on canine mesenchymal stem cells” The 4th Annual Comparative and Experimental Medicine Research Symposium UT, Knoxville, TN June 14-15, 2010, poster #64
- Rathore K and Cekanova M#: “Effects of environmental carcinogen, benzo(a)pyrene, on canine adipose-derived mesenchymal stem cells” the World Stem Cell Summit, San Diego, December 4-6th, 2013 poster #30367
- Treatment of Elbow Osteoarthritis with Bone-Marrow Derived Stem Cells
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